19343 Sonoma Highway (NW Corner of West Spain Street and Sonoma Highway) - The Ben Mitchell Adobe or Bianchini Adobe (1850)

19380 Sonoma Highway (NE Corner of West Spain Street and Sonoma Highway) - Blue Moon Saloon

796 West Spain Street - private commercial structure

SE Corner of West Spain Street at Fifth Street West or 410 Fifth Street West - adobe house (circa 1950s) - former Robert Thorup home who restored it from about 2007 to 2010 - private residence

420 West Spain Street - Ramekins Cooking School & Conference Center, a rammed earth structure

400 West Spain Street - Estate Restaurant (originally The Haraszthy-Vallejo House, home of Attila Haraszthy and Natalia Vallejo Haraszthy, daughter of General Mariano Guadalupe Vallejo and later The Scheiblich House) (circa 1870's)

West Spain Street at Third Street West - The Alameda at Lachryma Montis, an avenue of cottonwood trees some of which were planted in the 1850's (part of Sonoma Historic State Park)

West Spain Street at Third Street West - Lachryma Montis, The General M. G. Vallejo Residence (circa 1850) - Sonoma State Park (California Historical Landmark No. 4) (part of Sonoma Historic State Park)

West Spain Street at Third Street West - The Swiss Chalet - the storehouse of General Mariano Guadalupe Vallejo (circa 1852) (part of Sonoma Historic State Park)

West Spain Street at Third Street West - behind Lachryma Montis, The General M. G. Vallejo Residence, is located the water storage tank for Sonoma's city water supply

SE Corner of West Spain Street and Third Street West at 295 West Spain Street - Mission Revival style structure - private residence

275 West Spain Street - neo-Victorian structure designed and built by Robert Garant who formerly resided there - private residence

252 West Spain Street - First Congregational Church (shared with Congregation Shir Shalom) (built in 1873 and moved to present site in 1960 from the corner of Broadway and Patten Street)

181 West Spain Street - former Conley Residence - private residence

180 West Spain Street - Weyl House (circa 1870s) - former Churchill Residence - private residence (note; this structure was moved in the 1960s from 144 West Spain Street)

172 West Spain Street - Victorian structure - private residence

171 West Spain Street - 'An Inn 2 Remember' - Bed & Breakfast - former residence - Victorian style - commercial structure

164 West Spain Street - A. Weyl House - private offices and apartments (circa 1882)

157 West Spain Street - Craftsman structure - Private Residence

154 West Spain Street - entrance to Park Villas development

144 West Spain Street - development consisting of several apartment units (circa 1960s)

143 West Spain Street - The Vallejo-Castenada Adobe (circa 1842), also called The Demler-Jones-Vallejo Adobe, Casa Castenada and La Casita, the private residence of Robert and Leslie Demler

132 West Spain Street - K. Weyl home - Victorian structure- private residence

122 West Spain Street - Roche Winery Tasting Room - former residence - craftsman style - commercial structure

NW Corner of West Spain Street and First Street West at 110 West Spain Street - Sonoma Hotel - formerly Weyl Hall (circa 1880) - commercial structure

NW Corner of West Spain Street and First Street West - Marcus Vaca Adobe (circa 1847) - pulled down for the Weyl Building in the 1870's

SW Corner of West Spain Street and First Street West at 405 First Street West - El Dorado Hotel and El Dorado Kitchen (replica of the 1851 adobe structure after the original built by Salvador Vallejo)

SW Corner of West Spain Street and First Street West at 405 First Street West - site of the 1851 adobe structure, built by Salvador Vallejo, that was damaged in 1906 earthquake and then replaced by a non-adobe replica

SW corner of West Spain Street and First Street West at 421 First Street West - Sunflower Caffé - commercial building (the south portion of the Salvador Vallejo Adobe)

SW corner of West Spain Street and First Street West at 423 First Street West - Baksheesh - retail store (the south portion of the Salvador Vallejo Adobe)

NE Corner of West Spain Street and First Street West at 40 West Spain Street - Summer Vine retail store - commercial building

38 West Spain Street - commercial structure - The Candlestick - site of the Sebastiani Bus Depot Entrance (1938) - retail store

30 West Spain Street - Cuneo Apartments, formerly Sebastiani Apartments (1938) (site of the western portion of the 1836 Salvador Vallejo Residence) - commercial structure

30 West Spain Street - site of the western portion of the 1836 Salvador Vallejo Residence - pulled down in 1938 for the Sebastiani (now Cuneo) Apartments

18 West Spain Street - Swiss Hotel & Restaurant (circa 1836 - 1850) (The Reeger Adobe, formerly a Salvador Vallejo Property) (California Historical Landmark No. 496) - commercial structure

8 West Spain Street - Mary's Pizza (formerly Sonoma Post Office and part of site of Casa Grande) - commercial structure

2 West Spain Street - Sonoma Cheese Factory (formerly the site of Casa Grande, the 1835 Mariano Guadalupe Vallejo Residence) - commercial structure

2 West Spain Street (approximate) - site of Casa Grande and Tower - Home of General and Mrs. Mariana Guadalupe Vallejo (begun in 1835, occupied in 1837, burned down in 1867)

20 East Spain Street - Servants Quarters for Casa Grande (begun in 1835) (part of Sonoma Historic State Park)

20 East Spain Street - Toscano Hotel (1858, enlarged in 1870's) (part of Sonoma Historic State Park)

20 East Spain Street - Toscano Hotel Dining and Kitchen (part of Sonoma Historic State Park)

20 East Spain Street - Toscano Hotel Annex (circa1870's) (part of Sonoma Historic State Park)

One Sonoma Plaza - Sonoma City Hall (1906-08), the north (rear) facade is facing Spain Street

Sonoma Plaza at West Spain Street and First Street East - Bear Flag Monument (dedicated June 14, 1914)

SE Corner of East Spain Street and First Street East at 400 First Street East - Sonoma Mission Creamery building - commercial structure

NW Corner of East Spain Street and First Street East - Barracks for the Presidio de Sonoma (circa 1836) (part of Sonoma Historic State Park)

NE Corner of East Spain Street and First Street East - El Camino Real Bell signifying the northern end of California's El Camino Real (1910)

NE Corner of East Spain Street and First Street East - Mission San Francisco Solano Chapel (1823) (part of Sonoma State Historic Park) (California Historical Landmark No. 3)

NE Corner of East Spain Street and First Street East - Memorial to deceased Native Americans

130, 138, 146 East Spain Street - Victorian structures on the site of the original Mission San Francisco Solano main church - originally dwellings for stonemasons who worked at the Schocken Hill Quarry - three private residences

East Spain Street - Site of Mission Vineyards

133 East Spain Street - The Blue Wing Inn Adobe, originally called Sonoma House (circa 1848-52) (part of Sonoma Historic State Park)

147 East Spain Street

SW Corner of East Spain Street and Second Street East at XXX Second Street East

196 East Spain Street - The Pinelli Building or The Rubble House, now Anne Appleman's Florist (1906) - commercial structure

NW Corner of East Spain Street and Second Street East at 196 East Spain Street - Castagnasso House and Barn (circa 1870) - barn and horse pasture - private residence

SE Corner of East Spain Street and Second Street East or 205 East Spain Street - The Ray-Adler Adobe (1850) - private residence - Ned Forrest & Leslie Whitelaw home

NE Corner of East Spain Street and Second Street East or 206 East Spain Street - Victor Conforti home - private residence

220 East Spain Street - Adam Adler House - private residence

227 East Spain Street - Gaese Residence (circa 1857-58), private residence of P. B. MacNaughton

236 East Spain Street - A. Jones home - Adler Furniture Factory, later owned by Dikinis Family - private residence

245 East Spain Street - Cooke House (date unknown) - private residence

256 East Spain Street - Castagnasso House - Also know as Adam Adler's first store (circa 1848) - private residence

275 East Spain Street - Trinity Episcopal Church

At the East end of East Spain Street at 389 Fourth Street East - Sebastiani Winery

East End of East Spain Street - Site of The Archibald Tenant Adobe

East End of East Spain Street - Site of the Richard Maupin Adobe